Products

anti- RELN antibody

FNab07235 Catalogue No.
Host:
Rabbit
Reactivity:
Human
Isotype:
IgG
Tested Application:
ELISA, IHC
Product Information
Product Name
anti- RELN antibody
Catalogue No.
FNab07235
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation(By similarity).
Immunogen Information
Immunogen
reelin
Observed MW
62 kDa
Application
Tested Application
ELISA, IHC
Recommended dilution
IHC: 1:20-1:200
Uniprot information
UniProt ID
P78509
Images
Immunohistochemistry of paraffin-embedded human liver cancer using FNab07235(RELN antibody) at dilution of 1:200