HeLa cells were subjected to SDS PAGE followed by western blot with FNab07095(RALBP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat heart using FNab07095(RALBP1 antibody) at dilution of 1:100
Background
RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).