PTGER3 antibody

Synonyms:EP3 antibody, EP3 I antibody, EP3 II antibody, EP3 III antibody, EP3 IV antibody, EP3e antibody, PGE receptor EP3 subtype antibody, PGE2 R antibody, PGE2 receptor EP3 subtype antibody, Prostanoid EP3 receptor antibody, PTGER3 antibody
Catalogue No.:FNab06915Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PTGER3 antibody
Catalogue No.
FNab06915
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
prostaglandin E receptor 3(subtype EP3)
Alternative Names
EP3 antibody, EP3 I antibody, EP3 II antibody, EP3 III antibody, EP3 IV antibody, EP3e antibody, PGE receptor EP3 subtype antibody, PGE2 R antibody, PGE2 receptor EP3 subtype antibody, Prostanoid EP3 receptor antibody, PTGER3 antibody
UniProt ID
P43115
Observed MW
48 kDa
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06915(PTGER3 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab06915(PTGER3 Antibody) at dilution of 1:200
Background
Receptor for prostaglandin E2(PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems(By similarity).