Products
PTCH1 antibody
- Product Name
- PTCH1 antibody
- Catalogue No.
- FNab06910
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- patched homolog 1
- Alternative Names
- HPE7 antibody, NBCCS antibody, Patched antibody, patched homolog 1 antibody, Patched1 antibody, Protein patched homolog 1 antibody, PTC antibody, PTC1 antibody, PTCH antibody, PTCH1 antibody, PTCH11 antibody
- UniProt ID
- Q13635
- Observed MW
- 161 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:50-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06910(PTCH1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human liver using FNab06910(PTCH1 antibody) at dilution of 1:50
- Background
- Acts as a receptor for sonic hedgehog(SHH), indian hedgehog(IHH) and desert hedgehog(DHH). Associates with the smoothened protein(SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
