PSMA2 antibody

Synonyms:Proteasome subunit alpha type-2|Macropain subunit C3|Multicatalytic endopeptidase complex subunit C3|Proteasome component C3|PSMA2|HC3|PSC3 antibody
Catalogue No.:FNab06862Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PSMA2 antibody
Catalogue No.
FNab06862
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
proteasome (prosome, macropain) subunit, alpha type, 2
Alternative Names
Proteasome subunit alpha type-2|Macropain subunit C3|Multicatalytic endopeptidase complex subunit C3|Proteasome component C3|PSMA2|HC3|PSC3 antibody
UniProt ID
P25787
Observed MW
26 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab06862(PMSA2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophagus using FNab06862(PSMA2 antibody) at dilution of 1:50
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.