Products
PPP4C antibody
- Product Name
- PPP4C antibody
- Catalogue No.
- FNab06733
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein phosphatase 4 (formerly X), catalytic subunit
- Alternative Names
- Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C antibody, Pp4)|Protein phosphatase X (PP-X)|PPP4C|PPP4|PPX antibody
- UniProt ID
- P60510
- Observed MW
- 36 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06733(PPP4C antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gastric cancer using FNab06733(PPP4C antibody) at dilution of 1:100
- Background
- In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.
