K-562 cells were subjected to SDS PAGE followed by western blot with FNab06731(PPP3R1 antibody) at dilution of 1:1000
IP Result of anti-PPP3R1 (IP:FNab06731, 3ug; Detection:FNab06731 1:300) with HeLa cells lysate 5000ug.
Immunohistochemistry of paraffin-embedded human prostate using FNab06731(PPP3R1 antibody) at dilution of 1:100
Background
Protein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/ threonine protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C, Calcineurin A) and one regulatory subunit (PPP3R, Calcineurin B). PPP3R has two isoforms, PPP3R1 and PPP3R2. PPP3Rl is ubiquitously expressed in different tissues and is coded by the PPP3R1 gene which was mapped recently to human chromosome 2. PPP3Rl has four functional calcium-binding sites.