Products
PIK3CA antibody
- Product Name
- PIK3CA antibody
- Catalogue No.
- FNab06418
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- phosphoinositide-3-kinase, catalytic, alpha polypeptide
- Alternative Names
- Phosphatidylinositol 4 antibody, 5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha antibody, PI3K-alpha antibody, PI3Kalpha antibody, PtdIns-3-kinase subunit alpha)|Phosphatidylinositol 4 antibody, 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha antibody, p110alpha)|Phosphoinositide 3-kinase alpha|Phosphoinositide-3-kinase catalytic alpha polypeptide|Serine/threonine protein kinase PIK3CA|PIK3CA antibody
- UniProt ID
- P42336
- Observed MW
- 110 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab06418(PIK3CA antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab06418(PIK3CA antibody) at dilution of 1:50
- Background
- Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4, 5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.
