Products
PHKG2 antibody
- Product Name
- PHKG2 antibody
- Catalogue No.
- FNab06395
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- phosphorylase kinase, gamma 2 (testis)
- Alternative Names
- Phosphorylase b kinase gamma catalytic chain antibody, liver/testis isoform (PHK-gamma-LT antibody, PHK-gamma-T)|PSK-C3|Phosphorylase kinase subunit gamma-2|PHKG2 antibody
- UniProt ID
- P15735
- Observed MW
- 46 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab06395(PHKG2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab06395(PHKG2 antibody) at dilution of 1:100
- Background
- Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
