Products
PFTK1 antibody
- Product Name
- PFTK1 antibody
- Catalogue No.
- FNab06344
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- PFTAIRE protein kinase 1
- Alternative Names
- CDK14 antibody, hPFTAIRE1 antibody, KIAA0834 antibody, PFTAIRE protein kinase 1 antibody, PFTAIRE1 antibody, PFTK1 antibody
- UniProt ID
- O94921
- Observed MW
- 48-53 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:50-1:500
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06344(PFTK1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab06344(PFTK1 Antibody) at dilution of 1:200
- Background
- PFTK1 is a Cdc2-related protein kinase, also named as PFTAIRE1, CDK14 and belongs to the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. It acts as a cyclin-dependent kinases that regulates cell cycle progression and cell proliferation. The PFTK1 protein shows high homology with mouse Pftaire1, a Cdc2-related protein expressed primarily in the postnatal and adult nervous system(PMID:9202329). The protein contains 2 predicted nuclear localization signals that the N-terminal nuclear localization signals do not play a role in vivo(PMID:11313143). It has 3 isoforms produced by alternative splicing. This antibody is specific to PFTK1.
