anti- PFKM antibody
FNab06341
Catalogue No.
- Synonyms:
- GSD7, PFK 1, PFK A, PFK M, PFKM, PFKX, Phosphofructokinase 1, Phosphofructokinase M, phosphofructokinase, muscle, Phosphohexokinase
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Isotype:
- IgG
- Tested Application:
- ELISA, WB, IHC
Product Information
- Product Name
- anti- PFKM antibody
- Catalogue No.
- FNab06341
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
- Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Immunogen Information
- Immunogen
- phosphofructokinase, muscle
- Synonyms
- GSD7, PFK 1, PFK A, PFK M, PFKM, PFKX, Phosphofructokinase 1, Phosphofructokinase M, phosphofructokinase, muscle, Phosphohexokinase
- Observed MW
- 85 kDa
Application
- Tested Application
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
- UniProt ID
- P08237
Images
- Image 1
-
Immunohistochemistry of paraffin-embedded human esophageal cancer using FNab06341 (PFKM Antibody) at dilution of 1:100
- Image 4
-
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab06341 (PFKM antibody) at dilution of 1:1000