human liver tissue were subjected to SDS PAGE followed by western blot with FNab06327(PEX14 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab06327(PEX14 antibody) at dilution of 1:50
Background
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.