Products

PER2 antibody

Synonyms:FASPS antibody, hPER2 antibody, KIAA0347 antibody, PER2 antibody, period homolog 2 antibody
Catalogue No.:FNab06312Reativity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PER2 antibody
Catalogue No.
FNab06312
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
period homolog 2
Alternative Names
FASPS antibody, hPER2 antibody, KIAA0347 antibody, PER2 antibody, period homolog 2 antibody
UniProt ID
O15055
Observed MW
136 kDa
Application
Tested Applications
ELISA, WB, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000
Validated Images
BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab06312(PER2 antibody) at dilution of 1:600
IP Result of anti-PER2 (IP:FNab06312, 3ug; Detection:FNab06312 1:300) with HEK-293 cells lysate 1000ug.
Background
PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.