Products
PDCD4 antibody
- Product Name
- PDCD4 antibody
- Catalogue No.
- FNab06239
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- programmed cell death 4(neoplastic transformation inhibitor)
- Alternative Names
- Programmed cell death protein 4|Neoplastic transformation inhibitor protein|Nuclear antigen H731-like|Protein 197/15a|PDCD4|H731 antibody
- UniProt ID
- Q53EL6
- Observed MW
- 56 kDa
Application
- Tested Applications
- ELISA, WB, IHC, FC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06239(PDCD4 antibody) at dilution of 1:3000
IP Result of anti-PDCD4 (IP:FNab06239, 4ug; Detection:FNab06239 1:3000) with HeLa cells lysate 4000ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06239(PDCD4 antibody) at dilution of 1:50
- Background
- Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).
