anti- PARP1 antibody
FNab06151
Catalogue No.
- Synonyms:
- ADPRT, PPOL
- Host:
- Rabbit
- Reactivity:
- Human, Rat
- Isotype:
- IgG
- Tested Application:
- ELISA, WB, IHC
Product Information
- Product Name
- anti- PARP1 antibody
- Catalogue No.
- FNab06151
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
- This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Immunogen Information
- Immunogen
- poly (ADP-ribose) polymerase 1
- Synonyms
- ADPRT, PPOL
- Observed MW
- 115 kDa
Application
- Tested Application
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Uniprot information
- UniProt ID
- P09874
Images
- Image 1
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Immunohistochemistry of paraffin-embedded human breast cancer using FNab06151 (PARP1 antibody) at dilution of 1:100
- Image 4
-
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06051 (PARP1 Antibody) at dilution of 1:1000