Products

anti- PAR2 antibody

FNab06145 Catalogue No.
Synonyms:
F2RL1, G protein coupled receptor 11, GPR11, PAR 2, PAR2, Thrombin receptor like 1
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Isotype:
IgG
Tested Application:
ELISA, WB
Product Information
Product Name
anti- PAR2 antibody
Catalogue No.
FNab06145
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Proteinase-activated receptors (PARs) are G protein-coupled receptors activated through cleavage of their N-termini by mainly serine proteases. The family of PARs include four members: PAR1, PAR2, PAR3 and PAR4. PAR2, also known as F2RL1, is expressed in epithelial cells (e.g., lung, gastrointestinal tract) , endothelial cells, smooth muscle cells, fibroblasts, nerves, and some immune and inflammatory cells. PAR2 knockout mice and PAR2 agonists and antagonists have implicated PAR2 as a promising target in inflammatory conditions; respiratory, gastrointestinal, metabolic, cardiovascular, and neurological dysfunction; and cancers. (PMID:23895492)
Immunogen Information
Immunogen
coagulation factor II (thrombin) receptor-like 1
Synonyms
F2RL1, G protein coupled receptor 11, GPR11, PAR 2, PAR2, Thrombin receptor like 1
Observed MW
50 kDa
Application
Tested Application
ELISA, WB
Recommended dilution
WB: 1:200-1:2000
Uniprot information
UniProt ID
P55085
Images
COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab06145 (F2RL1 Antibody) at dilution of 1:600