Products
p120 Catenin antibody
- Product Name
- p120 Catenin antibody
- Catalogue No.
- FNab06059
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- catenin, delta 1
- Alternative Names
- CAS antibody, Catenin delta 1 antibody, CTNND antibody, CTNND1 antibody, KIAA0384 antibody, p120 antibody, p120 Catenin antibody, p120(cas) antibody, p120(ctn) antibody, P120CAS antibody, p120-catenin antibody, P120CTN antibody
- UniProt ID
- O60716
- Observed MW
- 105kd,66kd
Application
- Tested Applications
- ELISA, WB, IF, IP,IHC
- Recommended dilution
- WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100
Validated Images
RAW264.7 cells were subjected to SDS PAGE followed by western blot with FNab06059(p120 Catenin antibody) at dilution of 1:500
IP Result of anti-p120 Catenin (IP:FNab06059, 4ug; Detection:FNab06059 1:500) with mouse brain tissue lysate 2640ug.
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab06059(p120 Catenin antibody) at dilution of 1:200
- Background
- Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway(By similarity). Associates with and regulates the cell adhesion properties of both C-, E-and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
