NR1H2 antibody

Synonyms:Liver X receptor beta antibody, LXR b antibody, LXRB antibody, NER antibody, NER I antibody, NR1H2 antibody, Nuclear receptor NER antibody, Oxysterols receptor LXR beta antibody, RIP15 antibody, UNR antibody
Catalogue No.:FNab05834Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
NR1H2 antibody
Catalogue No.
FNab05834
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
nuclear receptor subfamily 1, group H, member 2
Alternative Names
Liver X receptor beta antibody, LXR b antibody, LXRB antibody, NER antibody, NER I antibody, NR1H2 antibody, Nuclear receptor NER antibody, Oxysterols receptor LXR beta antibody, RIP15 antibody, UNR antibody
UniProt ID
P55055
Observed MW
50 kDa, 40 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:200-1:2000
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab05834(NR1H2 antibody) at dilution of 1:500
Background
Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing(DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism(By similarity). Exhibits a ligand-dependent transcriptional activation activity(PubMed:25661920).