Products
NDE1 antibody
- Product Name
- NDE1 antibody
- Catalogue No.
- FNab05600
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nudE nuclear distribution gene E homolog 1 (A. nidulans)
- Alternative Names
- Nuclear distribution protein nudE homolog 1 (NudE)|NDE1|NUDE antibody
- UniProt ID
- Q9NXR1
- Observed MW
- 39 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
A2780 cells were subjected to SDS PAGE followed by western blot with FNab05600(NDE1 antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human breast cancer using FNab05600(NDE1 antibody) at dilution of 1:100
- Background
- This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.
