Products
NANOS3 antibody
- Product Name
- NANOS3 antibody
- Catalogue No.
- FNab05542
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- nanos homolog 3(Drosophila)
- Alternative Names
- Nanos homolog 3 antibody, nanos homolog 3 (Drosophila) antibody, NANOS1L antibody, NANOS3 antibody, NOS 3 antibody, NOS3 antibody
- UniProt ID
- P60323
- Observed MW
- 26-30 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:50-1:500
Validated Images
mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab05542(NANOS3 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab05542(NANOS3 Antibody) at dilution of 1:200
- Background
- Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and-independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells(PGCs) from apoptosis.
