human liver tissue were subjected to SDS PAGE followed by western blot with FNab05048(MCCC2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab05048(MCCC2 antibody) at dilution of 1:100
Background
This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.