Products
MBD2 antibody
Category:
Research Area:
- SPECIFICATIONS
- FIGURES
- CONDITIONS
- Product Name
- MBD2 antibody
- Catalogue No.
- FNab05034
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- methyl-CpG binding domain protein 2
- Alternative Names
- Methyl-CpG-binding domain protein 2|Demethylase (DMTase)|Methyl-CpG-binding protein MBD2|MBD2 antibody
- UniProt ID
- Q9UBB5
- Observed MW
- 43-45 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images

- Background
- Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.