LBP antibody

Synonyms:LBP antibody
Catalogue No.:FNab04712Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF, FC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
LBP antibody
Catalogue No.
FNab04712
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
lipopolysaccharide binding protein
Alternative Names
LBP antibody
UniProt ID
P18428
Observed MW
66 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, FC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab04712(LBP antibody) at dilution of 1:1000
IP Result of anti-LBP (IP: FNab04712, 4ug; Detection: FNab04712 1:1000) with mouse liver tissue lysate 3000ug.
Immunohistochemistry of paraffin-embedded human liver cancer using FNab04712(LBP antibody) at dilution of 1:50
Immunofluorescent analysis of L02 cells using FNab04712 (LBP antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
Background
Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides(LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria(PubMed:7517398, PubMed:24120359). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide(PubMed:7517398, PubMed:24120359).