Products

anti- IL1 Beta antibody

FNab04210 Catalogue No.
Synonyms:
IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta
Host:
Mouse
Reactivity:
Human
Isotype:
IgG1
Tested Application:
ELISA, IHC, WB
Product Information
Product Name
anti- IL1 Beta antibody
Catalogue No.
FNab04210
Size
100µg
Form
liquid
Purification
Protein G purified
Purity
≥95% as determined by SDS-PAGE
Host
Mouse
Clonality
monoclonal
Isotype
IgG1
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Immunogen Information
Immunogen
interleukin 1, beta
Synonyms
IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta
Observed MW
35kDa
Application
Tested Application
ELISA, IHC, WB
Recommended dilution
WB: 1:1000-1:4000; IHC: 1:50-1:500
Uniprot information
UniProt ID
P01584
Images
Immunohistochemistry of paraffin-embedded human lung cancer using FNab04210(IL1B antibody) at dilution of 1:200
A431 cells were subjected to SDS PAGE followed by western blot with FNab04210( IL1B Antibody) at dilution of 1:2000