Products
IL1 Beta antibody
- Product Name
- IL1 Beta antibody
- Catalogue No.
- FNab04210
- Size
- 100μg
- Form
- liquid
- Purification
- Protein G purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 9G5
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interleukin 1, beta
- Alternative Names
- IL1 beta antibody, Catabolin antibody, IL 1 antibody, IL 1 beta antibody, IL1 BETA antibody, IL1B antibody, IL1beta antibody, IL1F2 antibody, IL-1β antibody, Interleukin 1 beta antibody, interleukin 1 antibody, beta antibody
- UniProt ID
- P01584
- Observed MW
- 35kDa
Application
- Tested Applications
- ELISA, IHC, WB
- Recommended dilution
- WB: 1:1000-1:4000; IHC: 1:50-1:500
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab04210( IL1B Antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab04210(IL1B antibody) at dilution of 1:200
- Background
- The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
