HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04179(IGFBP4 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab04179(IGFBP4 antibody) at dilution of 1:100
Background
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.