Products
IFITM1 antibody
- Product Name
- IFITM1 antibody
- Catalogue No.
- FNab04140
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- interferon induced transmembrane protein 1(9-27)
- Alternative Names
- CD225 antibody, IFI17 antibody
- UniProt ID
- P13164
- Observed MW
- 17-19 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab04140(IFITM1 antibody) at dilution of 1:500
IP Result of anti-IFITM1 (IP:FNab04140, 4ug; Detection:FNab04140 1:500) with ROS1728 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded human lymphoma using FNab04140(IFITM1 antibody) at dilution of 1:50
- Background
- IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and hepatitis C virus(HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.
