Products
HTRA2 antibody
- Product Name
- HTRA2 antibody
- Catalogue No.
- FNab04070
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- HtrA serine peptidase 2
- Alternative Names
- HtrA serine peptidase 2 antibody, HTRA2 antibody, OMI antibody, PARK13 antibody, PRSS25 antibody, Serine protease 25 antibody, Serine proteinase OMI antibody
- UniProt ID
- O43464
- Observed MW
- 36 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04070(HTRA2 antibody) at dilution of 1:2000
IP Result of anti-HTRA2 (IP:FNab04070, 4ug; Detection:FNab04070 1:500) with Raji cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab04070(HTRA2 antibody) at dilution of 1:100
- Background
- Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
