HSP90AB1 antibody

Synonyms:HSP90B antibody, HSPC2 antibody, HSPCB antibody
Catalogue No.:FNab04053Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF, FC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HSP90AB1 antibody
Catalogue No.
FNab04053
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
heat shock protein 90kDa alpha(cytosolic), class B member 1
Alternative Names
HSP90B antibody, HSPC2 antibody, HSPCB antibody
UniProt ID
P08238
Observed MW
83-90kd
Application
Tested Applications
ELISA, WB, IHC, IF, FC, IP
Recommended dilution
WB: 1:2000-1:10000; IP: 1:500-1:1000; IHC: 1:250-1:1000; IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04053(HSP90AB1 antibody) at dilution of 1:1000
IP Result of anti-HSP90AB1 (IP: FNab04053, 4ug; Detection: FNab04053 1:700) with NIH/3T3 cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab04053(HSP90AB1 antibody) at dilution of 1:50
Immunofluorescent analysis of HepG2 cells, using FNab04053(HSP90AB1 antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Background
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.