Products

HSP90 antibody

Synonyms:HSP 86 antibody, HSP86 antibody, Hsp89 antibody, HSP89A antibody, HSP90 antibody, HSP90A antibody, HSP90AA1 antibody, HSP90N antibody, HSPC1 antibody, HSPCA antibody, HSPCAL1 antibody, HSPCAL4 antibody, HSPN antibody, LAP2 antibody
Catalogue No.:FNab04051Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IF, IHC, IP, WB, FC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HSP90 antibody
Catalogue No.
FNab04051
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
heat shock protein 90kDa alpha(cytosolic), class A member 1
Alternative Names
HSP 86 antibody, HSP86 antibody, Hsp89 antibody, HSP89A antibody, HSP90 antibody, HSP90A antibody, HSP90AA1 antibody, HSP90N antibody, HSPC1 antibody, HSPCA antibody, HSPCAL1 antibody, HSPCAL4 antibody, HSPN antibody, LAP2 antibody
UniProt ID
P07900
Observed MW
90 kDa
Application
Tested Applications
ELISA, IF, IHC, IP, WB, FC
Recommended dilution
WB: 1:1000-1:6000IP:1:500-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04051(HSP90 Antibody) at dilution of 1:3000
IP Result of anti-HSP90 (IP: FNab04051, 4ug; Detection: FNab04051 1:500) with K-562 cells lysate 4000ug.
Immunohistochemistry of paraffin-embedded human liver cancer using FNab04051(HSP90 antibody) at dilution of 1:50
Background
HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.