Products

anti- HSP47 antibody

FNab04045 Catalogue No.
Synonyms
47 kDa heat shock protein, AsTP3, CBP1, CBP2, Collagen binding protein, Colligin, gp46, HSP47, PIG14, PPROM, RA A47, Serpin H1, SERPINH1, SERPINH2
Host
Rabbit
Reactivity
Human, Mouse
Isotype
IgG
Tested Application
ELISA, IHC, WB, IF
Product Information
Product Name
anti- HSP47 antibody
Catalogue No.
FNab04045
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Immunogen Information
Immunogen
serpin peptidase inhibitor, clade H (heat shock protein 47) , member 1, (collagen binding protein 1)
Synonyms
47 kDa heat shock protein, AsTP3, CBP1, CBP2, Collagen binding protein, Colligin, gp46, HSP47, PIG14, PPROM, RA A47, Serpin H1, SERPINH1, SERPINH2
Observed MW
Refer to figures
Application
Tested Application
ELISA, IHC, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Uniprot information
UniProt ID
P50454
Images
Immunohistochemistry of paraffin-embedded human hepatocirrhosis tissue slide using FNab04045 (SERPINH1 Antibody) at dilution of 1:50
Immunofluorescent analysis of HeLa cells using FNab04045( SERPINH1 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L)
HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab04045 (SERPINH1 antibody) at dilution of 1:1000