HSP27 antibody

Synonyms:Heat shock protein beta 1 antibody, HSP 27 antibody, Hsp25 antibody, HSP27 antibody, HSP28 antibody, HSPB1 antibody
Catalogue No.:FNab04044Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB,IHC,IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
HSP27 antibody
Catalogue No.
FNab04044
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
heat shock 27kDa protein 1
Alternative Names
Heat shock protein beta 1 antibody, HSP 27 antibody, Hsp25 antibody, HSP27 antibody, HSP28 antibody, HSPB1 antibody
UniProt ID
P04792
Observed MW
27 kDa
Application
Tested Applications
ELISA, WB,IHC,IF
Recommended dilution
WB: 1:500-1:3000; IHC: 1:50-1:500; IF: 1:10-1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab04044(HSPB1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04044(HSP27 antibody) at dilution of 1:200
Background
HSPB1, also known as heat shock protein 27(Hsp27), belongs to the small heat shock protein family which is induced in response to environmental challenges or/and developmental transitions. It is also an anti-apoptotic protein that plays crucial roles in tumorigenesis and cell survival and is reported to be an independent prognosis marker for cancer. Recently HSPB1 has been found to be a valuable marker for melanoma. In addition to the predicted 27 kDa, an extra 50-55 kDa representing dimeric form of HSPB1 may also be observed.(21353161)