mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab04006(HPSE2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab04006(HPSE2 antibody) at dilution of 1:50
Background
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.