Products

anti- HAX1 antibody

FNab03765 Catalogue No.
Synonyms:
FLJ17042, FLJ18492, FLJ93803, HAX 1, HAX1, HCLS1 associated protein X 1, HCLSBP1, HS1 associating protein X 1, HS1 binding protein 1, HS1BP1, HSP1BP 1, SCN3
Host:
Rabbit
Reactivity:
Human, Mouse
Isotype:
IgG
Tested Application:
ELISA, WB, IHC, IF
Product Information
Product Name
anti- HAX1 antibody
Catalogue No.
FNab03765
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
HCLS1 associated protein X-1
Synonyms
FLJ17042, FLJ18492, FLJ93803, HAX 1, HAX1, HCLS1 associated protein X 1, HCLSBP1, HS1 associating protein X 1, HS1 binding protein 1, HS1BP1, HSP1BP 1, SCN3
Observed MW
36 kDa
Application
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Uniprot information
UniProt ID
O00165
Images
Immunohistochemistry of paraffin-embedded mouse heart using FNab03765 (HAX1 antibody) at dilution of 1:50
Immunofluorescence analysis of A549 cells using FNab03765(HAX1 antibody). Blue: DAPI for nuclear staining.
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03765 (HAX1 Antibody) at dilution of 1:1000