GTF2IRD1 antibody

Synonyms:CREAM1 antibody, GTF3 antibody, MUSTRD1 antibody, RBAP2 antibody, WBSCR11 antibody, WBSCR12 antibody
Catalogue No.:FNab03716Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GTF2IRD1 antibody
Catalogue No.
FNab03716
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
GTF2I repeat domain containing 1
Alternative Names
CREAM1 antibody, GTF3 antibody, MUSTRD1 antibody, RBAP2 antibody, WBSCR11 antibody, WBSCR12 antibody
UniProt ID
Q9UHL9
Observed MW
145 kDa, 120 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03716(GTF2IRD1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human heart using FNab03716(GTF2IRD1 antibody) at dilution of 1:100
Background
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer(USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8(By similarity).