K-562 cells were subjected to SDS PAGE followed by western blot with FNab03712(GTF2H2 antibody) at dilution of 1:500
Background
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair(NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.