mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab03430(GFM1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse brain using FNab03430( GFM1 Antibody) at dilution of 1:50
Background
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.