Products

GATM antibody

Synonyms:AGAT antibody
Catalogue No.:FNab03368Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GATM antibody
Catalogue No.
FNab03368
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Alternative Names
AGAT antibody
UniProt ID
P50440
Observed MW
43 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab03368(GATM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab03368(GATM antibody) at dilution of 1:100
Background
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.