Products
GATM antibody
- Product Name
- GATM antibody
- Catalogue No.
- FNab03368
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- glycine amidinotransferase (L-arginine:glycine amidinotransferase)
- Alternative Names
- Glycine amidinotransferase antibody, mitochondrial|L-arginine:glycine amidinotransferase|Transamidinase|GATM|AGAT antibody
- UniProt ID
- P50440
- Observed MW
- 43 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab03368(GATM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using FNab03368(GATM antibody) at dilution of 1:100
- Background
- This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
