human brain tissue were subjected to SDS PAGE followed by western blot with FNab03347(GARS antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded mouse brain using FNab03347(GARS antibody) at dilution of 1:50
Background
This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.