GALC antibody

Synonyms:Galactocerebrosidase (GALCERase)|Galactocerebroside beta-galactosidase|Galactosylceramidase|Galactosylceramide beta-galactosidase|GALC antibody
Catalogue No.:FNab03305Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
GALC antibody
Catalogue No.
FNab03305
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
galactosylceramidase
Alternative Names
Galactocerebrosidase (GALCERase)|Galactocerebroside beta-galactosidase|Galactosylceramidase|Galactosylceramide beta-galactosidase|GALC antibody
UniProt ID
P54803
Observed MW
77 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03305(Galc antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gastric cancer using FNab03305(Galc antibody) at dilution of 1:100
Background
This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.