Products
GADD45GIP1 antibody
- Product Name
- GADD45GIP1 antibody
- Catalogue No.
- FNab03296
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- growth arrest and DNA-damage-inducible, gamma interacting protein 1
- Alternative Names
- MRPL59 antibody, PLINP1 antibody, PRG6 antibody
- UniProt ID
- Q8TAE8
- Observed MW
- 25-28kd
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab03296(GADD45GIP1 antibody) at dilution of 1:300
IP Result of anti-GADD45GIP1 (IP:FNab03296, 4ug; Detection:FNab03296 1:400) with mouse heart tissue lysate 4000ug.
- Background
- Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
