FCN1 antibody

Synonyms:Ficolin-1|Collagen/fibrinogen domain-containing protein 1|Ficolin-A|Ficolin-alpha|M-ficolin|FCN1|FCNM antibody
Catalogue No.:FNab03060Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
FCN1 antibody
Catalogue No.
FNab03060
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
ficolin (collagen/fibrinogen domain containing) 1
Alternative Names
Ficolin-1|Collagen/fibrinogen domain-containing protein 1|Ficolin-A|Ficolin-alpha|M-ficolin|FCN1|FCNM antibody
UniProt ID
O00602
Observed MW
38 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab03060(FCN1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human brain astrocytoma using FNab03060( FCN1 Antibody) at dilution of 1:100
Background
The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.