EPCAM antibody

Synonyms:GA733-2 antibody, M1S2 antibody, M4S1 antibody, MIC18 antibody, TACSTD1 antibody, TROP1 antibody
Catalogue No.:FNab02799Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
EPCAM antibody
Catalogue No.
FNab02799
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
epithelial cell adhesion molecule
Alternative Names
GA733-2 antibody, M1S2 antibody, M4S1 antibody, MIC18 antibody, TACSTD1 antibody, TROP1 antibody
UniProt ID
P16422
Observed MW
40 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab02799(EPCAM antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab02799(EPCAM antibody) at dilution of 1:100
Immunofluorescent analysis of A431 cells using FNab02799 ( EPCAM Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Background
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.