Products
ELAC2 antibody
- Product Name
- ELAC2 antibody
- Catalogue No.
- FNab02732
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- elaC homolog 2 (E. coli)
- Alternative Names
- HPC2 antibody
- UniProt ID
- Q9BQ52
- Observed MW
- 105 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab02732(ELAC2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophagus using FNab02732(ELAC2 antibody) at dilution of 1:100
- Background
- The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
