K-562 cells were subjected to SDS PAGE followed by western blot with FNab02387(DICER1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using FNab02387( DICER1 Antibody) at dilution of 1:200
Immunofluorescent analysis of HepG2 cells, using DICER1 antibody FNab02387 at 1:100 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Background
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.