BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab02321(DCN Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human ovary using FNab02321(DCN antibody) at dilution of 1:50
Immunofluorescent analysis of MCF-7 cells using FNab02321 (Decorin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
Background
Decorin is a member of the small leucine-rich proteoglycan family of proteins. Decorin interacts with type I collagen fibrils, thereby influencing the kinetics of fibril formation and the distance between adjacent collagen fibrils. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis.