DCTD antibody

Category: Research Area:
Synonyms：Deoxycytidylate deaminase|dCMP deaminase|DCTD antibody
Catalogue No.：FNab02273Reactivity：Human, Mouse, Rat
Host：RabbitTested Application：ELISA, WB, IHC
Clonality：polyclonalIsotype：IgG
Manual MSDS
  • SPECIFICATIONS
Product Name
DCTD antibody
Catalogue No.
FNab02273
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
dCMP deaminase
Alternative Names
Deoxycytidylate deaminase|dCMP deaminase|DCTD antibody
UniProt ID
P32321
Observed MW
23 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab02273(DCTD antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse kidney using FNab02273(DCTD antibody) at dilution of 1:100
Background
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
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