K-562 cells were subjected to SDS PAGE followed by western blot with FNab02246(DARS2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab02246(DARS2 antibody) at dilution of 1:100
Background
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).