Products
Cytokeratin 19 antibody
- Product Name
- Cytokeratin 19 antibody
- Catalogue No.
- FNab02209
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 2F9
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- keratin 19
- Alternative Names
- CK 19 antibody, CK19 antibody, Cytokeratin 19 antibody, K19 antibody, K1CS antibody, keratin 19 antibody, KRT19 antibody
- UniProt ID
- P08727
- Observed MW
- 44-50 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:50-1:500
Validated Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab02209(KRT19 Antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using FNab02209(KRT19 Antibody) at dilution of 1:200. heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
- Background
- The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
