Products
CYP24A1 antibody
- Product Name
- CYP24A1 antibody
- Catalogue No.
- FNab02151
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cytochrome P450, family 24, subfamily A, polypeptide 1
- Alternative Names
- 24 OHase antibody, CP24 antibody, CYP24 antibody, CYP24A1 antibody, Cytochrome P450 24A1 antibody, Cytochrome P450 CC24 antibody, P450 CC24 antibody, Vitamin D(3) 24 hydroxylase antibody
- UniProt ID
- Q07973
- Observed MW
- 59 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab02151(CYP24A1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney using FNab02151(CYP24A1 antibody) at dilution of 1:50
- Background
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
