Products
CYP1A1 antibody

Category:
Research Area:
- SPECIFICATIONS
- FIGURES
- CONDITIONS
- Product Name
- CYP1A1 antibody
- Catalogue No.
- FNab02147
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- cytochrome P450, family 1, subfamily A, polypeptide 1
- Alternative Names
- Cytochrome P450 1A1 (CYPIA1)|Cytochrome P450 form 6|Cytochrome P450-C|Cytochrome P450-P1|Hydroperoxy icosatetraenoate dehydratase|CYP1A1 antibody
- UniProt ID
- P04798
- Observed MW
- 63 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images


- Background
- This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms.